Protection of Human Subject Participants in Nursing Research Essay

Discussion Prompt

In Melnyk & Fineout-Overholt’s (2019) textbook Box 23.1 on page 682, select one of the Fifteen Ethical Principles of the Universal Declaration on Bioethics and Human Rights.

State the principle and describe the importance of the selected principle to ethical research. In addition, describe how a researcher would ensure that this principle would be protected for human subjects in a research study. Protection of Human Subject Participants in Nursing Research Essay


Citations: At least 3 high-level scholarly peer-reviewed references in APA format from within the last 5 years
Students should pls read the question well to ensure the questions asked are addressed.


Protection of Human Subject Participants in Nursing Research

The identified principle is consent, particularly informed consent. This principle is important in ethical nursing research because it ensures that the research participants have an informed choice on whether or not to participate in the study (Melnyk & Fineout-Overholt, 2019). This principle has its origins in the medical researches that harmed participants, especially the Nazi human experiments during World War II and Tuskegee Syphilis Study between 1932 and 1972. The Nazi human experiments were horrific for the human participants who were recruited without their consent. Following the end of World War II and with the awareness that Nazi physicians conducted horrific human experiments, Nuremberg Trials were conducted in which Nuremberg Code was presented with ten ethical principles to guide medical research. One of the principles that the Nuremberg Code insisted on was the informed consent. Although the code was in place, it did not offer enough protection for participants as was evidenced by the Tuskegee Syphilis Study the recruited men without their informed consent. The ethical violations in that research study led to the Belmont Report that further emphasized the need for informed consent in medical research (Annas, 2018).

A research can ensure that the principle of informed consent is applied by demonstrating the respond for the personal autonomy of the participants. This involves clarified to the participants that their participation is to further medical research that would benefit the whole community and not an individual. The clarification must indicate their participation is distinctive from receiving clinical care. In addition, the participant must be made aware of all the potential benefits and harms from the study. Even if the research is determined not to expose the participant to any harm, such that informed consent does not become a legal requirement, the researcher must still ensure that all important information is conveyed comprehensive in a manner that ensures respect for the autonomy of the participants (Grove & Gray, 2022).


Annas, G. J. (2018). Beyond Nazi War Crimes Experiments: The Voluntary Consent Requirement of the Nuremberg Code at 70. American Journal of Public Health, 108(1), 42-46.

Grove, S. K., & Gray, J. R. (2022). Understanding Nursing Research: Building an Evidence-Based Practice (8th ed.). Elsevier Inc.

Melnyk, B. M., & Fineout-Overholt, E. (2019). Evidence-Based Practice in Nursing and Healthcare: A Guide to Best Practice (4th ed.). Wolters Kluwer.

Protection of Human Subject Participants in Nursing Research Essay

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